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Gygel. Nonoxynol-9 Spermicide.

In stock
  • NHS approved for use without a prescription.
  • Nonoxynol-9 (N-9) based; hormone-free.
  • Instantly reversible contraception.
  • Must be used with a barrier contraceptive.
  • New larger 81ml tube.
Grouped product items
ImageProduct Name
Gygel N-9 Spermicide. Exp March 2020
Weight : 0.104 kgs
- +
  • Buy 2 for £14.70 each and save 25%
Vaginal Applicator For Contraceptive Gel - Single Pack
Weight : 0.020 kgs
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  • Buy 2 for £2.66 each and save 10%
Vaginal Applicator For Contraceptive Gel - 3-Pack
Weight : 0.030 kgs
- +
  • Buy 2 for £7.66 each and save 9%

using spermicide with diaphragm

Gygel is effective when used in conjunction with a barrier method of contraception such diaphragms or FemCap. When used together with these methods, the gel is effective on two levels.

First, the sticky consistency seals any gaps or cracks and provides additional suction to the barrier. Second, the chemical effect on sperm adds another layer of contraceptive protection, creating a safety net if any sperm should attempt to bypass the barrier.

Spread 3ml of Gygel in the dome of and around the rim of your diaphragm or FemCap. Insert the barrier, making sure that the tip of the cervix is sitting in the gel. Do not remove your diaphragm for at least six to eight hours after having sex, and in the case of additional acts of intercourse, make sure to re-apply Gygel using a vaginal applicator.

Refer to the manufactures instructions for use on your barrier contraceptive for more detailed instructions.

using spermicide with diaphragm

Gygel: UK's #1 Nonoxynol-9 based spermicide

You've decided to use a barrier contraceptive for your birth control plan, and health benefits are at the top of your list of why. No hormones, no side effects, and eco-friendly — what could be better.

Gygel contains 2% of the active chemical ingredient nonoxynol-9. The gel is applied in the dome and around the edges of your barrier contraceptive to help perfect the seal provided by the barrier device whilst additionally killing the sperm.

Gygel is colorless, orderless, and will not stain.

Summary of Product Characteristics

Top-ranked spermicide for use with diaphragms or cervical caps. This Nonoxynol-9 Spermicide Gel is NHS approved for use without a prescription. Large 81ml tube. For a natural alternative to Gygel, try ContraGel, the natural spermicide alternative.

Trade Name of the Medicinal Product: GYGEL Contraceptive Jelly

Qualitative and Quantitative Composition: The gel contains 2.0% w/w of nonoxynol-9.

Pharmaceutical Form: Vaginal gel.

Important Information Regarding Gygel Spermicide:

  • Gygel should only be used by adult women with consent from their GP or gynecologist.
  • Gygel is intended for use in conjunction with barrier methods of contraception such as condoms, diaphragms and cervical caps such as FemCap.
  • This product does not protect against HIV or any other sexually transmitted diseases (STDs). You should use a latex condom or abstain from sex in order to protect yourself from STD transmission.
  • If irritation or discoloration occurs on the vagina or the penis, discontinue use. If symptoms worsen or continue for more than 48 hours, seek medical attention.
  • If consumed orally, the surfactant properties of Gygel may cause gastric irritation.
  • Pregnant women and those that may be pregnant should not use Gygel.
  • Do not store above 25ºC.

Clinical Particulars

Therapeutic Indications: For use as a spermicidal contraceptive in conjunction with barrier methods of contraception.

Method of Administration: For vaginal use. For use by adult females only.

Posology: The gel should be spread over the surface of the barrier that will be in contact with the cervix, and on the rim. The barrier and spermicide must be allowed to remain undisturbed for at least six to eight hours after intercourse. A fresh application of gel must be made prior to any subsequent acts of intercourse within this period of time, without removing the barrier (A vaginal applicator should be used for inserting more gel.)Douching is not recommended, but if desired it should be deferred for at least six hours after intercourse.

Contraindications: Sensitivity to nonoxynol-9 or to any component of the preparation. Patients with absent vaginal sensation e.g. paraplegics and quadriplegics.

Special warnings and special precautions for use: Spermicidal intravaginal preparations are intended for use in conjunction with barrier methods of contraception such as condoms, diaphragms and cervical caps. Where avoidance of pregnancy is important, the choice of contraceptive method should be made in consultation with a doctor or a family planning clinic.This product does not protect against HIV (AIDS) or other sexually transmitted diseases (STDs). A latex condom should be used to protect against the spread of STDs. High frequency use of nonoxynol-9 has been reported to cause epithelial damage and increase the risk of HIV infection. Therefore women at risk of HIV/STD infection and who have multiple daily acts of intercourse should be advised to choose another method of contraception. Sexually active women should consider their individual HIV/STD infection risk when choosing a method of contraception. If vaginal or penile irritation occurs, discontinue use. If symptoms worsen or continue for more than 48 hours, seek medical attention.

Interactions with other medicines or other forms of interaction: None known.

Pregnancy and Lactation: There is no evidence from animal and human studies that nonoxynol-9 is teratogenic.Human epidemiological studies have not shown any firm evidence of adverse effects on a fetus, however some studies have shown that nonoxynol-9 may be embryo toxic in animals. This product should not be used if pregnancy is suspected or confirmed. Animal studies have detected nonoxynol-9 in milk after intravaginal administration. Use by lactating women has not been studied.

Effects on ability to drive and to use machines: None known.

Undesirable effects: May cause irritation of the vagina or penis.

Overdose: SeIf taken orally, the surfactant properties of this preparation may cause gastric irritation. General supportive therapy should be carried out. Hepatic and renal function should be monitored if medically indicated.

Pharmacological Properties

Pharmacodynamic properties: The standard in vitro test (Sander-Cramer) evaluating the effect of nonoxynol-9 on animal sperm motility has shown the compound to be a potent spermicide.The site of action of nonoxynol-9 has been determined as the sperm cell membrane.The lipoprotein membrane is disrupted, increasing permeability, with subsequent loss of cell components and decreased motility. A similar effect on vaginal epithelial and bacterial cells is also found.

Pharmacokinetic properties: The intravaginal absorption and excretion of radio labelled (14C) nonoxynol-9 has been studied in non-pregnant rats and rabbits and in pregnant rats. No appreciable difference was found in the extent or rate of absorption in pregnant and non-pregnant animals. Plasma levels peaked at about one hour and recovery from urine as unchanged nonoxynol-9 accounted for approximately 15-25% and faces approximately 70% of the administered dose as unchanged nonoxynol-9. Less than0.3% was found in the milk of lactating rats. No metabolites were detected in any of the samples analyzed.

Preclinical Safety Data: No relevant information additional to that contained elsewhere in the Summary of Product Characteristics.

Pharmaceutical Particulars

List of excipients: Methyl parahydroxybenzoate (E 218)Sorbitol solution (E 420)Lactic acidPovidone K30Propylene glycolSodium carboxymethylcelluloseSorbic acid (E 200)Purified water.

Incompatibilities (major): Not applicable.

Shelf-life: 2 years.

Special precautions for storage: Do not store above 25ºC.

Nature and contents of containers: Epoxy resin lined aluminum tubes with polyethylene caps. Available in 81 gram packs; an applicator is available separately if required.

Instructions for use/handling: Not applicable.

Administrative Data

Name and Address of Marketing Authorisation Holder: Marlborough Pharmaceuticals Ltd35A High StreetMarlboroughWiltsSN8 1LWUK

Marketing Authorisation Number: PL 23138/0010

Date of First Authorisation/Renewal of Authorisation:12 September 1995/17 July 1996

Date of (Partial) Revision of the Text: 14th July 2007Legal category GSL

More Information
Product SheetNot Available
Product VideosNot Available
What's It Used For?Adding another layer of protection when using a diaphragm or cervical cap. Seals the barrier and kills sperm.
NotesAlways read manufacturer's instructions before use.
Why Buy?Traditional Nonoxynol-9 spermicide gel. Necessary for effective use of diaphragms and cervical caps.
BrandOther Brands

Gygel is a Nonoxynol 9 based spermicide gel. It is designed to be used together with a barrier contraceptive. The questions compiled below are in no way a substitute to reading the Gygel manufactures instructions or the manufactures instructions you received with your diaphragm, Caya, or FemCap.

Are there any hormones in Gygel?

No. Gygel is 100% hormone-free. It is also referred to as an "instantly reversible form contraception" because the contraception is only effective for one instance of intercourse and does not have any effect on further acts of intercourse. This gives you the power to keep choosing to use contraception, or to cease using contraception, each time you have sex.

Do I need a prescription in order to buy Gygel?

No. To purchase Gygel from in the UK, no prescription is needed. Gygel is an over-the-counter (OTC) medicine.

However, it must be used as part of a barrier contraceptive method, and not as birth control on its own. Diaphragms do require a prescription because precise sizing is critical for effectiveness. FemCap and Caya diaphragms do not need to be sized and therefore do not need a prescription.

Are there alternative Nonoxynol-9 spermicides available in the UK?

No. There are currently no other spermicidal contraceptive gels containing N-9 available in the UK. ContraGel is the natural spermicide allterntive and is 100% N-9 free.

What side effects are associated with Gygel?

Side effects of Gygel can affect both the male and female partner. The most commonly reported side effects are irritation, burning, or itchiness of the vagina or penis. An increase in urinary tract infections and yeast infections in women can also often be traced to spermicide use.

Is there an alternative to Gygel that will allow me to keep using my barrier contraceptive if I am experiencing side effects from the spermicide?

Yes. ContraGel is the perfect solution for those experiencing side effects from Nonoxynol-9 spermicides.

Can I use Gygel if I'm pregnant?

If you are already pregnant there is no point in using Gygel; using it is not recommended. You should always inform your doctor if you are pregnant or planning a pregnancy before using any medication, including Gygel.

Can I use this spermicide if I'm breastfeeding?

There is no reason not to use spermicide while breastfeeding. Many women choose to avoid hormones while they are breastfeeding, and spermicide is often part of a non-hormonal birth control solution While Gygel is probably a safe choice, no studies have been conducted regarding the safety or effectiveness of using Gygel while breastfeeding. Always seek medical advice from your doctor or midwife, or look into the natural spermicide alternative Contragel.

Can I use Gygel if I'm taking other medications?

Yes, spermicide is not known to effect other medication.

Should I use Gygel every time I have intercourse, throughout my cycle?

cyclotest can identify your fertility windowNot necessarily. The goal of barrier contraception is to prevent sperm from reaching and fertilizing an egg. But an egg is only viable for about 24 hours out of the month during ovuation, and sperm is only viable for about 5 days.

This means that conception can only occur during a short window of time each month known as the 'fertile window'. Therefore, your 7 day per month 'fertile window' is the only time contraception is necessary to prevent pregnancy.

Why use your barrier the entire month if the risk of pregnancy only lasts 7 days?

While an in-depth understanding of ovulation and sperm life span is enlightening, relying on an unequivocal knowledge of your fertile window to plan or prevent pregnancy is a huge responsibility. It takes hard work and dedication. Cyclotest fertility monitors make the process 100 times more attainable. You can become an expert in your individual cycle and achieve your personal family planning goals with confidence and ease.

Orders received before 2pm on working days are usually shipped that day, or the next working day.

UK & N.Ireland with Registered Mail: £3,95 (3-5 days) or Courier: £5,95 (1-2 days, excl' bulk orders)

Spain & Portugal shipped usually within 1-2 working day of sending. Shipping Cost: £4,95 (excl' bulk orders)
Rest of Europe usually 3-5 working days after sending. Shipping Cost: £9,95 < 1 kilo
Everywhere else with Registered Mail, allow for about a week or more. Cost: £15  < 1 kilo